BiCo

Hands-On Demonstrator Series: Napari-KICS

Date
Oct 27, 2022
Time
1:00 PM - 2:00 PM
Speaker
Arne Ludwig
Language
en
Main Topic
Biologie
Other Topics
Informatik
Description
Chromosome-scale genome assembly is affected by scaffolding errors and may yield incorrect chromosome sizes. Today, we present KICS, a semi-automated and cost-efficient approach for examining the validity of the assembly by estimating relative chromosome sizes from the respective karyotype images. The method employs threshold-based image segmentation and uses the extracted chromosome areas as proxies for the actual chromosome sizes. The suitability of the approach is confirmed by a strong correlation between area and DNA content evaluated on karyotype images of varied species and achieving a 6 Mb chromosome size error on a reference human karyotype dataset.
Links

Last modified: Oct 17, 2022, 10:17:40 AM

Location

TUD Andreas-Pfitzmann-Bau (Computer Science) (Room: 1020 )Nöthnitzer Straße4601069Dresden
Homepage
https://navigator.tu-dresden.de/etplan/apb/00

Organizer

Center for Scalable Data Analytics and Artificial Intelligence (ScaDS.AI)Chemnitzer Straße46b, 2. OG01187Dresden
Phone
+49 351 463-40900
E-Mail
ScaDS.AI
Homepage
https://scads.ai
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