Hands-On Demonstrator Series: Napari-KICS
- Date
- Oct 27, 2022
- Time
- 1:00 PM - 2:00 PM
- Speaker
- Arne Ludwig
- Language
- en
- Main Topic
- Biologie
- Other Topics
- Informatik
- Description
- Chromosome-scale genome assembly is affected by scaffolding errors and may yield incorrect chromosome sizes. Today, we present KICS, a semi-automated and cost-efficient approach for examining the validity of the assembly by estimating relative chromosome sizes from the respective karyotype images. The method employs threshold-based image segmentation and uses the extracted chromosome areas as proxies for the actual chromosome sizes. The suitability of the approach is confirmed by a strong correlation between area and DNA content evaluated on karyotype images of varied species and achieving a 6 Mb chromosome size error on a reference human karyotype dataset.
- Links
Last modified: Oct 17, 2022, 10:17:40 AM
Location
TUD Andreas-Pfitzmann-Bau (Computer Science) (Room: 1020
)Nöthnitzer Straße4601069Dresden
- Homepage
- https://navigator.tu-dresden.de/etplan/apb/00
Organizer
Center for Scalable Data Analytics and Artificial Intelligence (ScaDS.AI)Chemnitzer Straße46b, 2. OG01187Dresden
- Phone
- +49 351 463-40900
- ScaDS.AI
- Homepage
- https://scads.ai
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