BiMe

Coordination of progenitor specification and growth in the developing spinal cord

date
22.11.2018 
time
04:00 PM - 05:00 PM 
speaker
Prof. Anna Kicheva 
affiliation
Institute of Science and Technology Austria 
part of series
BIOTEC Green Seminar 
language
en 
main topic
Biology: general
subtopics
Medicine: Regeneration
host
Dr. Julieta Aprea 
abstract

AbstractDuring tissue development morphogen signaling controls both pattern formation and tissue growth. In turn the profiles of morphogen activity depend on the molecular and biophysical properties of tissues. The goal of our research is to unravel the feedbacks between cell fate specification, tissue growth and morphogen signaling in the developing spinal cord. Understanding how these processes are coordinated will provide insight into how the reproducibility and accuracy of spinal cord development is achieved.
5 most recent papers
Decoding of position in the developing neural tube from antiparallel morphogen gradients. Zagorski M, Tabata Y, Brandenberg N, Lutolf MP, Tkacik G, Bollenbach T, Briscoe J, Kicheva A. Science (2017) 356(6345):1379-1383.
The roles of negative feedback and Gli regulation in the dynamics of Shh signaling. Cohen M, Kicheva A, Ribeiro A, Blassberg R, Page K, Briscoe J. Nature Comm. (2015): 6, 6709.
Coordination of progenitor specification and growth in mouse and chick spinal cord. Kicheva A, Bollenbach T, Ribeiro A,Valle HP, Rovell-Badge R, Episkopou V, Briscoe J. Science (2014): 345 (6204):1254927.
Developmental pattern formation: insights from physics and biology. Kicheva A, Cohen M, Briscoe J. Science (2012): 338, 210.
Kinetics of morphogen gradient formation. Kicheva A§, Pantazis P§, Bollenbach T§, Kalaidzidis Y, Bittig T, Jülicher F & González-Gaitán M. Science (2007): 315, 521-5.

 

Last update: 16.11.2018 00:08.

venue 

DFG Center for Regenerative Therapies Dresden (CRTD, auditorium left) 
Fetscherstraße 105
01307 Dresden
telefon
+49 (0)351 458 82064 
fax
+49 (0)351 458 82059  
e-mail
DFG Center for Regenerative Therapies Dresden 
homepage
http://www.crt-dresden.de 

organizer 

DFG Center for Regenerative Therapies Dresden (CRTD)
Fetscherstraße 105
01307 Dresden
telefon
+49 (0)351 458 82064 
fax
+49 (0)351 458 82059 
e-mail
DFG Center for Regenerative Therapies Dresden (CRTD) 
homepage
http://www.crt-dresden.de 
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