Towards Large Scale Reconstruction of Neuro-Anatomy at Nanometer Resolution
- Date
- Feb 25, 2013
- Time
- 2:00 PM - 3:00 PM
- Speaker
- Dipl.-Medieninf. Stephan Saalfeld
- Language
- en
- Main Topic
- Informatik
- Other Topics
- Informatik
- Description
- A classic method for high resolution neuronal circuit reconstruction is to image a volume of neuronal tissue as a series of ultra-thin sections, each as a mosaic of overlapping tiles. In order to reconstruct the volume, the individually prepared and imaged sections need to be re-assembled into a continous 3d space. Each section and tile may be deformed significantly. I describe a new registration method that simultaneously maximizes the overlap of corresponding regions and minimizes the deformation applied to each single image through a global elastic constraint. The method has been used to automatically restore large Electron Microscopy section series consisting of more than 33,000 individual images.
Last modified: Feb 25, 2013, 8:38:36 AM
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TUD Andreas-Pfitzmann-Bau (Computer Science) (INF 1096)Nöthnitzer Straße4601069Dresden
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TUD InformatikNöthnitzer Straße4601069Dresden
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