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UID:DSC-21140
DTSTART;TZID=Europe/Berlin:20241205T130000
SEQUENCE:1733380581
TRANSP:OPAQUE
DTEND;TZID=Europe/Berlin:20241205T140000
URL:https://www.dresden-science-calendar.de/calendar/en/detail/21140
LOCATION:B CUBE\, Tatzberg 4101307 Dresden
SUMMARY:CMCB Life Sciences Seminar: Prof. David Rueda\, Imperial College Lo
 ndon\, MRC Laboratory of Medical Sciences\, UK
CLASS:PUBLIC
DESCRIPTION:Speaker: \nInstitute of Speaker: \nTopics:\nWillkommen\, Biolog
 ie\n Location:\n  Name: B CUBE ()\n  Street: Tatzberg 41\n  City: 01307 Dr
 esden\n  Phone: +49 351 463 43000\n  Fax: +49 351 463 40322\nDescription: 
 <p><strong>Host:</strong> Michael Schlierf (B CUBE)</p> <p><strong>Title:<
 /strong> \"Single Molecule Dynamics of Protein Nucleic Acids: From Gene Ed
 iting to Chromatin Remodelling\"</p> <p><strong>Abstract: </strong>The Rue
 da Lab investigates the molecular mechanisms that regulate epigenetic proc
 esses involved in human diseases\, such as cancer and neurodegenerative di
 sorders. To this aim\, we develop and apply single-molecule approaches to 
 image the structural dynamics of protein-nucleic acid complexes across sca
 les (from molecules to cells). We are particularly interested in elucidati
 ng various mechanistic aspects of chromatin processing and gene expression
  regulation\, such as chromatin structure and remodeling\, DNA damage and 
 repair\, and gene editing. In this seminar\, I will present our latest fin
 dings on how CRISPR/Cas9 finds off-targets and the chromatin remodeling me
 chanism of ySWR1. </p>
DTSTAMP:20260416T001854Z
CREATED:20240620T053950Z
LAST-MODIFIED:20241205T063621Z
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