Bi

Network Dynamics as an Inverse Problem --Detecting network size and topology from time series

Date
Oct 19, 2023
Time
11:00 AM - 12:00 PM
Speaker
Marc Timme
Affiliation
Institute for Theoretical Physicsand Center for Advancing Electronics Dresden (cfaed), TU Dresden
Series
MPI-CBG Thursday Seminar
Language
en
Main Topic
Biologie
Host
Carl Modes
Description
The dynamics of biological networks enables the function of a variety of systems, including metabolic, gene-regulatory and neural circuits. To date, it remains unclear how to extract key features of networks if only time series data from (some) units are available. Here we report on recent progress on detecting structural features from observed dynamics. First, we demonstrate how to identify the number N of dynamical variables making up a network -- arguably its most fundamental property -- from recorded time series of only a small subset of n<N variables. Second, we sketch approaches to uncover network topological features from observed nodal time series data. We demonstrate first steps of applying the general theoretical methods developed to simulated models of biological and artifical systems. This is work with Jose Casadiego, Mor Nitzan, Hauke Haehne, Georg Boerner and others. [1] Topical Review: Marc Timme & Jose Casadiego, J. Phys. A 47:343001 (2014). [2] Casadiego et al., Nature Comm. 8:2192 (2017). [3] Nitzan et al., Science Adv. 3:e1600396 (2017). [4] Haehne et al., Phys. Rev. Lett. 122:158301 (2019).

Last modified: Oct 20, 2023, 7:40:35 AM

Location

Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG Auditorium (big half))Pfotenhauerstraße10801307Dresden
Phone
+49 351 210-0
Fax
+49 351 210-2000
E-Mail
MPI-CBG
Homepage
http://www.mpi-cbg.de

Organizer

Max Planck Institute of Molecular Cell Biology and GeneticsPfotenhauerstraße10801307Dresden
Phone
+49 351 210-0
Fax
+49 351 210-2000
E-Mail
MPI-CBG
Homepage
http://www.mpi-cbg.de
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