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CMCB Life Sciences Seminar: Deconstruction thymus development to reconstruct immunity from human pluripotent stem cells

Date
Jan 30, 2020
Time
1:00 PM - 2:00 PM
Speaker
René Maehr
Affiliation
University of Massachusetts Medical School
Series
CMCB Life Sciences Seminar
Language
en
Main Topic
Medizin
Other Topics
Medizin
Host
Max Yun
Description

5 most important publications:



Min SY, Desai A, Yang Z, Sharma A, DeSouza T, Genga RMJ, Kucukural A, Lifshitz LM, Nielsen S, Scheele C, Maehr R, Garber M, Corvera S. Diverse repertoire of human adipocyte subtypes develops from transcriptionally distinct mesenchymal progenitor cells. *Proc Natl Acad Sci U S A*. 2019 Aug 16.



Genga RMJ, Kernfeld EM, Parsi KM, Parsons TJ, Ziller MJ, Maehr R. Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development. *Cell Reports*. 2019 Apr 16; 27(3):708-718.e10.



Fischer DS, Fiedler AK, Kernfeld EM, Genga RMJ, Bastidas-Ponce A, Bakhti M, Lickert H, Hasenauer J, Maehr R. Inferring population dynamics from single-cell RNA-sequencing time series data. *Nat Biotechnol*. 2019 04; 37(4):461-468.



Kernfeld EM, Genga RMJ, Neherin K, Magaletta ME, Xu P, Maehr R. A Single-Cell Transcriptomic Atlas of Thymus Organogenesis Resolves Cell Types and Developmental Maturation.*Immunity*. 2018 Jun 19; 48(6):1258-1270.e6.



Parsi KM, Hennessy E, Kearns N, Maehr R. Using an Inducible CRISPR-dCas9-KRAB Effector System to Dissect Transcriptional Regulation in Human Embryonic Stem Cells. *Methods Mol Biol*. 2017; 1507:221-233.



Everybody is very welcome!

Links

Last modified: Jan 28, 2020, 12:10:10 AM

Location

Center for Regenerative Therapies Dresden (CRTD, ground floor, auditorium left)Fetscherstraße10501307Dresden
Phone
+49 (0)351 458 82064
Fax
+49 (0)351 458 82059
E-Mail
TUD CRTD
Homepage
http://www.crt-dresden.de

Organizer

Center for Molecular and Cellular Bioengineering (CMCB)01062Dresden
Phone
+49 351 463-40359
Fax
+49 351 463-40322
E-Mail
TUD CMCB
Homepage
https://tu-dresden.de/cmcb
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