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Influence of natural and synthetic nanomaterials on bone regeneration

Date
Dec 13, 2019
Time
1:00 PM - 2:00 PM
Speaker
Prof.Dr. Barbara Kaltschmidt
Affiliation
Department of Cell Biology, Faculty of Biology,University of Bielefeld
Language
en
Main Topic
Materialien
Host
Kristina Krummer
Description
Bone regeneration is a highly orchestrated process crucial for endogenous healing procedures after accidents, infections or tumor therapy.

Changes in surface nanotopography are known to directly affect the formation of osteogenic cell types, although no direct linkage to the endogenous nanotopography of bone was described so far. I will present the presence of pores of 31.93 ± 0.97 nm diameter on the surface of collagen type I fibers, the organic component of bone, and demonstrate these pores to be sufficient to induce osteogenic differentiation of several adult human stem cell types. SiO2 nanoparticles, biomimicing 31.93 ± 0.97 nm pores, were able to induce osteogenic differentiation of stem cells in vitro also.

In addition I will show the regenerative potential of several nanomaterials to drive calvarial bone regeneration in vivo in a cell-and growth factor free manner.
Links

Last modified: Dec 6, 2019, 12:05:30 AM

Location

Leibniz Institut für Festkörper- und Werkstoffforschung Dresden (D2E.27, IIN)Helmholtzstraße2001069Dresden
Homepage
http://www.ifw-dresden.de

Organizer

Leibniz Institut für Festkörper- und Werkstoffforschung DresdenHelmholtzstraße2001069Dresden
Homepage
http://www.ifw-dresden.de
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