Bi

Quantifying morphogenesis - Ectodermal organ formation as a case study

Date
Dec 4, 2019
Time
11:00 AM - 12:00 PM
Speaker
Jeremy Green
Affiliation
King's College London, UK
Language
en
Main Topic
Biologie
Host
Jacqueline Tabler
Description
Perceptions of morphogenesis are dominated by two ideas: local growth by cell proliferation and epithelial bending by active cell shape change, especially apical constriction. Examination of ectodermal organs, including teeth, salivary glands, hair follicles and mammary glands, reveals that other cell behaviours drive their formation. In particular, active cell migration and rearrangement are the active processes early on, while at later stages active basal constriction is required, overturning previous models implicating proliferation-driven morphogenesis. A systematic, quantitative analytical framework for morphogenesis is proposed.

Last modified: Oct 22, 2019, 12:05:25 AM

Location

Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG Galleria)Pfotenhauerstraße10801307Dresden
Phone
+49 351 210-0
Fax
+49 351 210-2000
E-Mail
MPI-CBG
Homepage
http://www.mpi-cbg.de

Organizer

Max Planck Institute of Molecular Cell Biology and GeneticsPfotenhauerstraße10801307Dresden
Phone
+49 351 210-0
Fax
+49 351 210-2000
E-Mail
MPI-CBG
Homepage
http://www.mpi-cbg.de
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