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UID:DSC-15067
DTSTART;TZID=Europe/Berlin:20190321T110000
SEQUENCE:1553213155
TRANSP:OPAQUE
DTEND;TZID=Europe/Berlin:20190321T120000
URL:https://www.dresden-science-calendar.de/calendar/en/detail/15067
LOCATION:MPI-CBG\, Pfotenhauerstraße 10801307 Dresden
SUMMARY:Miguel-Aliaga: Sex differences in organ plasticity
CLASS:PUBLIC
DESCRIPTION:Speaker: Irene Miguel-Aliaga\nInstitute of Speaker: MRC London 
 Institute of Medical Sciences\, Imperial College London\, London\, UK\nTop
 ics:\nBiologie\n Location:\n  Name: MPI-CBG (MPI-CBG Auditorium (big half)
 )\n  Street: Pfotenhauerstraße 108\n  City: 01307 Dresden\n  Phone: +49 3
 51 210-0\n  Fax: +49 351 210-2000\nDescription: Internal organs constantly
  exchange signals\, and can respond with profound anatomical and functiona
 l transformations\, even in fully developed organisms. Such organ plastici
 ty results from a need to integrate both environmental information and int
 ernal state\, and is key to maintaining homeostasis and adapting to challe
 nges. We seek to identify the mechanisms by which organs sense and respond
  to change: the molecules\, cellular events and physiological adaptations 
 involved. Some of our recent work has explored the physiological plasticit
 y of the intestinal epithelium using Drosophila and mice\, focusing on bot
 h stem cells and one their progeny: the digestive/absorptive enterocytes. 
 Our work has revealed unexpected sexual dimorphisms\, as well as intestina
 l contributions to reproductive success. I will discuss some of this work\
 , and will likely present unpublished findings on 1) new hormonal and neur
 onal mechanisms by which gonads make gut cells sexually dimorphic for “s
 elfish” reasons\, and/or 2) a novel intestinal micronutrient sensor that
  controls systemic food intake and growth rate by activating TOR signallin
 g.
DTSTAMP:20260628T210513Z
CREATED:20181002T000923Z
LAST-MODIFIED:20190322T000555Z
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