Collective feeding in worms: Quantitative phenotyping and modelling identifies behavioral rules underlying aggregation in C. elegans
- Date
- Feb 22, 2018
- Time
- 3:00 PM - 4:00 PM
- Speaker
- Linus Schumacher
- Affiliation
- Biological Physics, Imperial College London
- Series
- TUD ZIH Kolloquium
- Language
- en
- Main Topic
- Informatik
- Other Topics
- Biologie, Informatik
- Host
- Ralph Müller-Pfefferkorn, Zentrum für Informationsdienste und Hochleistungsrechnen
- Description
Collective behaviour is a hallmark of complex living systems. Often studied in groups of large animals or small cells, it less well understood at the mesoscopic scale. We investigate collective feeding of the nematode C. elegans, known for its easy genetic manipulation and stereotypic, yet complex behaviour. In this system, small genetic perturbations can lead to strikingly different population-level behaviours. We quantify behavioural differences between the „solitary“ lab strain and a „social“ aggregating mutant. To understand the mechanism of aggregation, we draw on concepts from motility-induced phase transitions and agent-based modelling. Finally, we investigate the potential benefits of collective feeding in an attempt to explain the predominance of aggregating strains in the wild.
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Last modified: Feb 22, 2018, 8:39:53 AM
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