Investigating the Genetics, Structure and Function of the Diseased Retina to Prepare for Clinical Trials

Datum

10.03.2015

Zeit

16:00 - 17:00

Sprecher

Hendrik Scholl, Wilmer Eye Institute, Johns Hopkins University, Baltimore

Serie

CMCB Life Sciences Seminar

Sprache

en

Hauptthema

Biologie

Andere Themen

Biologie, Medizin

Host

Marius Ader

Beschreibung

Information about the speaker:Hendrik Scholl is the director of the Retinal Degenerations Clinic of the Retina Division and the director of the Visual Neurophysiology Service. He is also the co-director of Wilmer’s newly founded Center for Stem Cells and Ophthalmic Regenerative Medicine (STORM). He specializes in medical and surgical management of retinal diseases such as age-related macular degeneration (AMD) and diabetic retinopathy. He has a specific expertise in inherited retinal degenerations and uses the latest diagnostic technology such as eletroretinography, microperimetry and high-resolution imaging. Dr. Scholl’s primaryresearch interest relates to visual loss in retinal degenerations and to therapeutic measures in order to rescue vision. In his leadership role of large multi-center clinical studies, he aims to develop better tools to prove therapeutic efficacy for upcoming clinical trials. Selected publications:1. Charbel Issa P, Gillies MC, Chew EY, Bird AC, Heeren TF, Peto T, Holz FG, Scholl HPN (2013). Macular telangiectasia type 2. Prog Retin Eye Res. 34: 49-77. 2. Weismann D, Hartvigsen K, Lauer N, Bennett KL, Scholl HPN, Charbel Issa P, Cano M, Brandstätter H, Tsimikas S, Skerka C, Superti-Furga G, Handa JT, Zipfel PF, Witztum JL, Binder CJ (2011) Complement factor H binds malondialdehyde epitopes and protects from oxidative stress. Nature 478: 76-81.3. Charbel Issa P, Troeger E, Finger R, Holz FG, Wilke R, Scholl HPN (2010) Structure-function correlation of the human central retina. PLoS One. 22;5(9): e12864.4. Scholl HPN, Charbel Issa P, Walier M, Janzer S, Pollok-Kopp B, Börncke F, Fritsche LG, Chong NV, Fimmers R, Wienker T, Holz FG, Weber BHF, Oppermann M (2008) Systemic complement activation in age-related macular degeneration. PLoS ONE 3(7):e2593.5. Scholl HPN, Bellmann C, Dandekar SS, Bird AC, Fitzke FW (2004) Photopic and scotopic fine matrix mapping of retinal areas of increased fundus autofluorescence in patients with age-related maculopathy. Invest Ophthalmol Vis Sci 45:574-583.

Links

• to announcement of the organizer

Letztmalig verändert: 10.03.2015, 09:01:36