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Analyzing surgical smoke by differential mobility spectrometry: From theory to clinical applications

Datum
05.11.2026
Zeit
13:00 - 15:00
Sprecher
Phillipp Müller
Zugehörigkeit
Faculty of Medicine and Health Technology Tampere, Finland
Serie
TUD nanoSeminar
Sprache
en
Hauptthema
Physik
Andere Themen
Physik
Host
Arezoo Dianat
Beschreibung
Most solid cancer tumors, such as breast cancer and brain tumors, are frequently treated by surgeries, in which only cancerous tissue should be removed. However, identifying the margin (i.e. border between tumor and healthy tissue) visually is at best challenging. For the surgical removal of tissue diathermy knifes or electric bipolar forceps are frequently used to decrease bleeding. The procedure produces surgical smoke that contains cell metabolites. An emerging and promising technique for molecular analysis of surgical smoke is differential mobility spectrometry (DMS), which employs an electric field consisting of an asymmetric oscillating high intensity field and a low static field component to obtain information on the electric field-mobility dependence of ions. One bottleneck for the widespread application of DMS for the analysis during tumor resection is the dependence of DMS measurements on environmental parameters such as humidity, temperature and pressure. This talk will present an overview on our recent work on distinguishing cancerous and non-cancerous tissue based on surgical smoke measured by DMS, with a focus on compensating the impact of environmental parameters on the DMS measurements.
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Letztmalig verändert: 12.06.2026, 07:35:22

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TUD Materials Science - HAL (HAL Bürogebäude - 115)Hallwachsstraße301069Dresden
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TUD Institute for Materials ScienceHallwachsstr.301069Dresden
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