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UID:DSC-21787
DTSTART;TZID=Europe/Berlin:20250313T110000
SEQUENCE:1741847781
TRANSP:OPAQUE
DTEND;TZID=Europe/Berlin:20250313T120000
URL:https://www.dresden-science-calendar.de/calendar/de/detail/21787
LOCATION:MPI-CBG\, Pfotenhauerstraße 10801307 Dresden
SUMMARY:Fuchs: Stem Cells: Acquiring\, Remembering and Recalling Past Exper
 iences
CLASS:PUBLIC
DESCRIPTION:Speaker: Elaine Fuchs\nInstitute of Speaker: Howard Hughes Medi
 cal Institute\, The Rockefeller University\, New York\nTopics:\n\n Locatio
 n:\n  Name: MPI-CBG (MPI-CBG CBG Large Auditorium)\n  Street: Pfotenhauers
 traße 108\n  City: 01307 Dresden\n  Phone: +49 351 210-0\n  Fax: +49 351 
 210-2000\nDescription: According to Webster\, memory “is the power or pr
 ocess of reproducing or recalling what has been learned and retained espec
 ially through associative mechanisms.”  It has generally been thought to
  be the privilege of the brain\, and indeed as most neurons are long-lived
 \, they have the capacity to store memories of their experiences and recal
 l them months later.  However many tissues of our body learn from their pa
 st experiences\, and like memories that occur in the brain\, tissue memori
 es have both beneficial and maladaptive consequences. An excellent example
  of this is our barrier epithelial tissues such as the skin\, lung and gut
 \, which are the first line of defense between our body and the outside wo
 rld.  These tissues harbor reservoirs of long-lived\, self-renewing stem c
 ells that rejuvenate the barrier during normal homeostasis and restore it 
 when damaged by wounds\,  mechanical stress\, ultraviolet radiation\, path
 ogens and irritants. How do epithelial stem cells equip themselves to cope
  with these harmful stresses? My laboratory discovered that when stem cell
 s encounter diverse stresses\, their chromatin develops and stores epigene
 tic memories with profound consequences.  We focus on dissecting the compl
 ex interactions between stem cells and their environment that are evolutio
 narily optimized for tissue fitness but go awry in chronic inflammation an
 d cancer.
DTSTAMP:20261010T084254Z
CREATED:20250308T063601Z
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