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Electronic Nano-biosensors Based on Graphene Transistors

Datum
04.07.2024
Zeit
13:00 - 15:00
Sprecher
Zhaoli Gao
Zugehörigkeit
Chinese University of Hong Kong
Serie
TUD nanoSeminar
Sprache
en
Hauptthema
Physik
Andere Themen
Physik
Host
Arezoo Dianat
Beschreibung
Probing biosystems with two-dimensional (2D) materials provides tremendous opportunities for highly sensitive detection of physiological properties at the molecular level, which can pave the way toward early-stage disease diagnosis and improved healthcare outcomes. In this talk, I will introduce the process we have developed for scalable fabrication of 2D-biosensor arrays for multiplexed detection of disease biomarkers, where a graphene field effect transistor (GFET) is utilized for signal transduction, and a biomolecular layer, e.g., protein, nuclide acid, serves as the biological recognition element. Further, integrating the hybridization chain reaction (HCR) process with GFET readout leads to oligonucleotide detection with sensitivity at the aM level. Looking to the future, I will discuss the synthesis of crystalline multilayer graphene and transition metal dichalcogenide materials with band gaps, providing a pathway toward next-generation biosensors with even greater sensitivity. Finally, I will discuss the ongoing development of a universal sensing platform based on aptamer-GFET biosensors that is potentially useful for wearable electronics for detecting health and performance biomarkers in sweat. Probing biosystems with two-dimensional (2D) materials provides tremendous opportunities for highly sensitive detection of physiological properties at the molecular level, which can pave the way toward early-stage disease diagnosis and improved healthcare outcomes. In this talk, I will introduce the process we have developed for scalable fabrication of 2D-biosensor arrays for multiplexed detection of disease biomarkers, where a graphene field effect transistor (GFET) is utilized for signal transduction, and a biomolecular layer, e.g., protein, nuclide acid, serves as the biological recognition element. Further, integrating the hybridization chain reaction (HCR) process with GFET readout leads to oligonucleotide detection with sensitivity at the aM level. Looking to the future, I will discuss the synthesis of crystalline multilayer graphene and transition metal dichalcogenide materials with band gaps, providing a pathway toward next-generation biosensors with even greater sensitivity. Finally, I will discuss the ongoing development of a universal sensing platform based on aptamer-GFET biosensors that is potentially useful for wearable electronics for detecting health and performance biomarkers in sweat.
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Letztmalig verändert: 12.06.2024, 07:40:15

Veranstaltungsort

TUD Materials Science - HAL (HAL Bürogebäude - 115)Hallwachsstraße301069Dresden
Homepage
https://navigator.tu-dresden.de/etplan/hal/00

Veranstalter

TUD Institute for Materials ScienceHallwachsstr.301069Dresden
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