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UID:DSC-20409
DTSTART;TZID=Europe/Berlin:20240201T110000
SEQUENCE:1706855785
TRANSP:OPAQUE
DTEND;TZID=Europe/Berlin:20240201T120000
URL:https://www.dresden-science-calendar.de/calendar/de/detail/20409
LOCATION:MPI-CBG\, Pfotenhauerstraße 10801307 Dresden
SUMMARY:Bruns: Biomedical Imaging beyond the Visible - Fluorescence Imaging
  in the Shortwave-Infrared 
CLASS:PUBLIC
DESCRIPTION:Speaker: Oliver Bruns\nInstitute of Speaker: NCT Dresden\nTopic
 s:\n\n Location:\n  Name: MPI-CBG (MPI-CBG Auditorium (big half))\n  Stree
 t: Pfotenhauerstraße 108\n  City: 01307 Dresden\n  Phone: +49 351 210-0\n
   Fax: +49 351 210-2000\nDescription: SWIR provides several advantages ove
 r the visible and near-infrared regions: general lack of autofluorescence\
 , low light absorption by blood and tissue\, and reduced scattering. In th
 is wavelength range tissues become translucent. Recent progress in detecti
 on technology and the development of probes demonstrated that\, in princip
 al\, SWIR imaging enables applications which were previously not feasible 
 with any other technique. These advantages will enable new capabilities in
  preclinical imaging. While the optical advantages are clear\, the success
 ful translation of SWIR imaging into routine applications requires novel\,
  bright and targeted probes as well as advanced imaging setups. Most SWIR 
 imaging setups so far are used for proof of principal demonstrations only.
  To utilize the full potential\, our first goal is developing novel SWIR i
 maging setups\, which enable high-speed intravital imaging\, ultra-sensiti
 ve whole animal imaging and fluorescence molecular tomography in mice in t
 he SWIR. Our second goal is to develop novel bright and targeted SWIR prob
 es for preclinical research in oncology.  The novel applications include S
 WIR imaging of physiology and metabolic activity and targeted SWIR imaging
  of tumors. SWIR intravital microscopy will allow imaging the brain vascul
 ature around tumors in mice through intact skin and skull and generating d
 etailed blood flow-maps in mice. In the future\, advantages of SWIR imagin
 g will also improve fluorescence guided surgery and other clinical applica
 tions in precision medicine. To advance clinical research and enable clini
 cians to utilize and benefit from the great potential of SWIR imaging\, th
 e overarching goal of us is to develop novel non- toxic SWIR probes for fu
 ture clinical use. The unprecedented sensitivity of SWIR imaging in combin
 ation with its deep penetration and high resolution should allow detecting
  cancer cells with very high sensitivity\, which is an ultimate goal for a
  surgeon.
DTSTAMP:20260710T162812Z
CREATED:20240103T063939Z
LAST-MODIFIED:20240202T063625Z
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