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UID:DSC-15070
DTSTART;TZID=Europe/Berlin:20190509T110000
SEQUENCE:1557439592
TRANSP:OPAQUE
DTEND;TZID=Europe/Berlin:20190509T120000
URL:https://www.dresden-science-calendar.de/calendar/de/detail/15070
LOCATION:MPI-CBG\, Pfotenhauerstraße 10801307 Dresden
SUMMARY:Miska: Inheritance beyond DNA sequence: news from worms and fishes
CLASS:PUBLIC
DESCRIPTION:Speaker: Eric Miska\nInstitute of Speaker: The Gurdon Institute
 \, University of Cambridge\, UK\nTopics:\n\n Location:\n  Name: MPI-CBG (M
 PI-CBG Auditorium (big half))\n  Street: Pfotenhauerstraße 108\n  City: 0
 1307 Dresden\n  Phone: +49 351 210-0\n  Fax: +49 351 210-2000\nDescription
 : Since August Weismann (1834-1914) formulated the distinction between inn
 ate and acquired characteristics at the end of the 19th century\, the deba
 te relating to the inheritance of acquired traits has raised many controve
 rsies in the scientific community. Following convincing arguments against 
 (e.g. William Bateson) this debate was then set aside by the majority of t
 he scientific community. However\, a number of epigenetic phenomena involv
 ing RNA\, histone modification or DNA methylation in many organisms have r
 enewed interest in this area. Transgenerational effects likely have wide-r
 anging implications for human health\, biological adaptation and evolution
 \, however their mechanism and biology remain poorly understood. We recent
 ly demonstrated that a germline nuclear small RNA/chromatin pathway can ma
 intain epi-allelic inheritance for many generations in C. elegans. We will
  discuss evidence for such inheritance in an emerging vertebrate model\, t
 he cichlid fish of Malawi.
DTSTAMP:20260705T110037Z
CREATED:20181002T000923Z
LAST-MODIFIED:20190509T220632Z
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