BEGIN:VCALENDAR VERSION:2.0 PRODID:www.dresden-science-calendar.de METHOD:PUBLISH CALSCALE:GREGORIAN X-MICROSOFT-CALSCALE:GREGORIAN X-WR-TIMEZONE:Europe/Berlin BEGIN:VTIMEZONE TZID:Europe/Berlin X-LIC-LOCATION:Europe/Berlin BEGIN:DAYLIGHT TZNAME:CEST TZOFFSETFROM:+0100 TZOFFSETTO:+0200 DTSTART:19810329T030000 RRULE:FREQ=YEARLY;INTERVAL=1;BYMONTH=3;BYDAY=-1SU END:DAYLIGHT BEGIN:STANDARD TZNAME:CET TZOFFSETFROM:+0200 TZOFFSETTO:+0100 DTSTART:19961027T030000 RRULE:FREQ=YEARLY;INTERVAL=1;BYMONTH=10;BYDAY=-1SU END:STANDARD END:VTIMEZONE BEGIN:VEVENT UID:DSC-12977 DTSTART;TZID=Europe/Berlin:20170615T150000 SEQUENCE:1501087039 TRANSP:OPAQUE DTEND;TZID=Europe/Berlin:20170615T160000 URL:https://www.dresden-science-calendar.de/calendar/de/detail/12977 LOCATION:TUD Willers-Bau\, Zellescher Weg 12-1401069 Dresden SUMMARY:Rulands: Emergence and universality in the regulation of cell fate CLASS:PUBLIC DESCRIPTION:Speaker: Steffen Rulands\nInstitute of Speaker: MPI PKS\, Dresd en\nTopics:\nBiologie\, Physik\, Informatik\n Location:\n Name: TUD Wille rs-Bau (Willersbau A317)\n Street: Zellescher Weg 12-14\n City: 01069 Dr esden\n Phone: \n Fax: \nDescription: The development of an organism rel ies on the tightly orchestrated interplay of many cells. How do these cell s build complex structures\, like the heart? In this talk\, I will show ho w collective dynamics emerge from the interaction of many molecules or cel ls\, and how such emergence contributes to the mechanistic understanding o f cell fate regulation. Combining single-cell genomics with statistical ph ysics I will first show how collective dynamics in the primary layer of ep igenetics - DNA methylation – may contribute to symmetry breaking in the early embryo. Moving from the molecular to the tissue scale I will then s how that collective cell behaviour in growing tissues gives rise to a self -similar\, “critical” dynamics of the progeny of marked cells\, result ing in tissue-independent (universal) dependencies in lineage tracing expe riments. Identifying these universalities provides the theoretical foundat ion to extract biological information from such experiments.
Since 2 017 Steffen Rulands is a group leader at the Max Planck Institute for the Physics of Complex Systems in Dresden. From 2003 to 2009 he studied physic s at the University of Constance and Technical University Munich. He obtai ned his Ph.D. in Theoretical Physics at Ludwig Maximilian University\, Mun ich. After two years as postdoc he became a Herchel Smith fellow at the Un iversity of Cambridge from 2015 to 2016. DTSTAMP:20260409T033550Z CREATED:20170519T074340Z LAST-MODIFIED:20170726T163719Z END:VEVENT END:VCALENDAR